The present manuscript describes simple, sensitive, rapid, accurate, precise and economical colorimetric method for the determination of tolperisone hydrochloride (TOL) in bulk and tablet dosage form. In this study a colorimetric method was used for determination of tolperisone hydrochloride by forming a colored chromogen. The measurements were carried out at wavelengths of 551 nm. The method was found to be linear (r2>0.991) in the range of 10-40 μg/ml for tolperisone hydrochloride. The limit of determination was 0.81 μg/ml and limit of quantification was 2.46 μg/ml for tolperisone hydrochloride. The method was successfully applied for simultaneous determination of tolperisone hydrochloride in tablet dosage form.
Loading....